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Health.cat news The New England Journal of Medicine: Search Results
The New England Journal of Medicine (NEJM) RSS feed -- Search Results. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Attention Deficit?Hyperactivity Disorder and Month of School Enrollment
31/12/69 - Variable rates of diagnosis and treatment of attention deficit?hyperactivity disorder (ADHD) across the United States have aroused concern about overdiagnosis, underdiagnosis, and appropriate treatment. Over the past two decades, rates of diagnosis and treatment of ADHD have increased. Among…

The FDA Sentinel Initiative ? An Evolving National Resource
31/12/69 - The Food and Drug Administration (FDA) Sentinel Initiative, which was launched in 2008, has matured from a pilot program designed to assess potential drug-safety signals in insurance claims into a core component of the agency?s evolving safety surveillance system. Sentinel is a flexible and robust…

Trauma-Informed Care ? Reflections of a Primary Care Doctor in the Week of the Kavanaugh Hearing
31/12/69 - Today, it was my third patient of the morning: a woman with a history of childhood sexual abuse and an abusive marriage. She shared with me her distress, her escalating nightmares and flashbacks over the past week. She held out her left arm to me, where for the first time since her adolescence, she…

Neoadjuvant PD-1 Blockade in Resectable Lung Cancer; Nivolumab and Ipilimumab in Advanced Melanoma; Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma; Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy; Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma; Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma; Nivolumab and Ipilimumab versus Ipilimumab in Untreated Melanoma; Rapid Eradication of a Bulky Melanoma Mass with One Dose of Immunotherapy; Genetic Basis for Clinical Response to CTLA-4 Blockade; Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma; Nivolumab plus Ipilimumab in Advanced Melanoma; Safety and Tumor Responses with Lambrolizumab (Anti?PD-1) in Melanoma; Hepatotoxicity with Combination of Vemurafenib and Ipilimumab
31/12/69 - Neoadjuvant PD-1 Blockade in Resectable Lung Cancer (Original Article, N Engl J Med 2018;378:1976-1986), Nivolumab and Ipilimumab in Advanced Melanoma (Correspondence, N Engl J Med 2017;377:2503-2504), Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma (Original Article, N…

Mutagenesis in Norovirus in Response to Favipiravir Treatment
31/12/69 - To the Editor: Chronic norovirus infection in immunocompromised patients can lead to malabsorption and other complications; currently, no treatment has proved to be effective. Favipiravir is an antiviral medication that has been approved for the treatment of influenza in Japan and has been used by…

Olaparib Desensitization in a Patient with Recurrent Peritoneal Cancer
31/12/69 - To the Editor: Olaparib, a poly(adenosine diphosphate [ADP]?ribose) polymerase (PARP) inhibitor, is a recommended and effective treatment option for patients who have relapsed, platinum-sensitive ovarian cancer, tubal cancer, or primary peritoneal cancer, regardless of BRCA mutation status.…

Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain
31/12/69 - To the Editor: Given the historically poor prognosis associated with brain metastases in patients with melanoma, better therapeutic options are needed. Can Tawbi et al. (Aug. 23 issue) address the following methodologic and logistic considerations pertaining to their study? Considering that 22% of…

Circulating Extracellular Vesicles in Human Disease
31/12/69 - To the Editor: Shah et al. (Sept. 6 issue) provided a comprehensive review of the role of extracellular vesicles in human disease and of their clinical implications. In the article, the discussion of the nucleic acids contained in extracellular vesicles focused only on RNAs (e.g. messenger RNAs…

Peripheral Nerve Blocks for Hand Procedures
31/12/69 - To the Editor: In their video, Chandrasoma et al. (Sept. 6 issue) clearly illustrate the procedures for peripheral nerve block of the hand, presenting the advantages and limitations of that technique. However, the use of ultrasound-guided nerve block is mentioned but not illustrated; the authors…

Case 37-2018: A 23-Year-Old Woman with Vision Loss
31/12/69 - Presentation of Case. Dr. Seth N. Levin (Neurology): A 23-year-old right-handed woman with a history of migraines was evaluated at this hospital for vertigo and vision loss affecting the right eye. Six days before admission, a right frontal headache and right retro-orbital pain developed; these…

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